{"id":19274,"date":"2026-10-21T17:44:36","date_gmt":"2026-10-21T20:44:36","guid":{"rendered":"https:\/\/www.fie.undef.edu.ar\/ceptm\/?p=19274"},"modified":"2026-10-21T17:44:36","modified_gmt":"2026-10-21T20:44:36","slug":"ee-uu-avanza-en-el-desarrollo-de-antidotos-contra-agentes-nerviosos-y-otras-armas-quimicas","status":"publish","type":"post","link":"https:\/\/www.fie.undef.edu.ar\/ceptm\/?p=19274","title":{"rendered":"EE.UU. avanza en el desarrollo de ant\u00eddotos contra agentes nerviosos y otras armas qu\u00edmicas"},"content":{"rendered":"<p>La Agencia de Reducci\u00f3n de Amenazas del Departamento de Defensa de EE.UU., avanza en un contrato de US$ 40 millones a las empresas Battelle y CMC Pharmaceuticals, destinado a desarrollar contramedidas m\u00e9dicas y ant\u00eddotos para proteger al personal militar contra agentes nerviosos y armas qu\u00edmicas. El programa consiste en un contrato de 5 a\u00f1os para presentar un nuevo f\u00e1rmaco, el que deber\u00e1 ser aprobado por la Administraci\u00f3n de Alimentos y Medicamentos (FDA) de ese pa\u00eds. La investigaci\u00f3n se centra en la creaci\u00f3n de reactivadores capaces de neutralizar neurotoxinas artificiales, mediante la restauraci\u00f3n de la Acetilcolinesterasa, una enzima clave que regula las se\u00f1ales nerviosas entre el cerebro, las gl\u00e1ndulas y los m\u00fasculos. Una vez completado, este tratamiento se distribuir\u00e1 a las FFAA estadounidenses y aliadas en kits sellados y listos para su empleo inmediato, proporcionando as\u00ed una capacidad m\u00e9dica estandarizada y disponible en los menores niveles, para hacer frente a amenazas qu\u00edmicas emergentes.<\/p>\n<hr \/>\n<p class=\"wp-block-paragraph\">Ohio biotech research organizations <a href=\"https:\/\/www.linkedin.com\/posts\/battelle-awarded-contract-to-enhance-airbase-share-7516452841859801090-HfNW\/?utm_source=share&amp;utm_medium=member_desktop&amp;rcm=ACoAACEHeU8BA7s3Zf7ijcKn7gErYlzOcebxbOk\" target=\"_blank\" rel=\"noreferrer noopener\">Battelle<\/a> and <a href=\"https:\/\/www.linkedin.com\/posts\/together-with-the-united-states-department-share-7516537975640395776-vGHt\/\" target=\"_blank\" rel=\"noreferrer noopener\">CMC Pharmaceuticals<\/a> have advanced work on a $40-million US Department of Defense initiative to develop medical countermeasures protecting military personnel from nerve agents.<\/p>\n<p class=\"wp-block-paragraph\">Awarded through the <a href=\"https:\/\/thedefensepost.com\/2026\/02\/26\/us-biohazard-control-battelle\/\" target=\"_blank\" rel=\"noreferrer noopener\">Defense Threat Reduction Agency\u2019s<\/a> Joint Science and Technology Office, the five-year program is now moving a promising solution toward Investigational New Drug submission with the US Food and Drug Administration.<\/p>\n<p class=\"wp-block-paragraph\">The effort centers on producing reactivators that can <a href=\"https:\/\/thedefensepost.com\/2024\/09\/10\/pentagon-anti-nerve-agent-battelle\/\" target=\"_blank\" rel=\"noreferrer noopener\">neutralize man-made neurotoxins<\/a> by restoring <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK539735\/\" target=\"_blank\" rel=\"noreferrer noopener\">acetylcholinesterase<\/a>, a critical enzyme that regulates neurotransmitters responsible for signals between neurons, glands, muscle cells, and the brain.<\/p>\n<figure id=\"attachment_19276\" aria-describedby=\"caption-attachment-19276\" style=\"width: 2048px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" class=\"size-full wp-image-19276\" src=\"https:\/\/www.fie.undef.edu.ar\/ceptm\/wp-content\/uploads\/2026\/10\/7493992-2048x1365-1.jpg\" alt=\"\" width=\"2048\" height=\"1365\" srcset=\"https:\/\/www.fie.undef.edu.ar\/ceptm\/wp-content\/uploads\/2026\/10\/7493992-2048x1365-1.jpg 2048w, https:\/\/www.fie.undef.edu.ar\/ceptm\/wp-content\/uploads\/2026\/10\/7493992-2048x1365-1-300x200.jpg 300w, https:\/\/www.fie.undef.edu.ar\/ceptm\/wp-content\/uploads\/2026\/10\/7493992-2048x1365-1-1024x683.jpg 1024w, https:\/\/www.fie.undef.edu.ar\/ceptm\/wp-content\/uploads\/2026\/10\/7493992-2048x1365-1-768x512.jpg 768w, https:\/\/www.fie.undef.edu.ar\/ceptm\/wp-content\/uploads\/2026\/10\/7493992-2048x1365-1-1536x1024.jpg 1536w\" sizes=\"(max-width: 2048px) 100vw, 2048px\" \/><figcaption id=\"caption-attachment-19276\" class=\"wp-caption-text\">Soldier simulates a check for radiation using an Identifier. Photo: Graham Snodgrass\/US Army<\/figcaption><\/figure>\n<p class=\"wp-block-paragraph\">Once completed, these reactivators are expected to be available in a sealed vial and be distributed to the US Armed Forces and its allies, establishing a standardized field-ready medical capability to enhance care for troops exposed to chemical threats.<\/p>\n<p class=\"wp-block-paragraph\">\u201cBattelle has a <a href=\"https:\/\/thedefensepost.com\/2026\/02\/26\/us-biohazard-control-battelle\/\" target=\"_blank\" rel=\"noreferrer noopener\">long history<\/a> of working with the [Department of Defense] to develop medical countermeasures that protect military personnel from chemical threats,\u201d <a href=\"https:\/\/www.battelle.org\/insights\/newsroom\/press-release-details\/battelle--cmc-pharmaceuticals-advance-medical-countermeasure-program-for-u.s.-department-of-war\" target=\"_blank\" rel=\"noreferrer noopener\">said<\/a> <strong>Drew Cawthon<\/strong>, business line director at Battelle.<\/p>\n<p class=\"wp-block-paragraph\">\u201cWe are proud to continue supporting this important mission and to continue to drive next-generation solutions to emerging threats with a strong partner like CMC Pharmaceuticals.\u201d<\/p>\n<p class=\"wp-block-paragraph\">CMC Pharmaceuticals assists on the program by handling chemistry, manufacturing, and controls tasks, including laboratory development, testing, formulation, and regulatory oversight.<\/p>\n<p class=\"wp-block-paragraph\">\u201cProviding drug development services to the [US Department of Defense] to protect our troops against the threat of nerve agents is truly an honor,\u201d said <strong>Mike Radomsky<\/strong>, president of CMC Pharmaceuticals.<\/p>\n<p class=\"wp-block-paragraph\">\u201cThis program adds to our existing and growing portfolio of improved therapeutics and medical countermeasures for the US government.\u201d<\/p>\n<p><strong>Fuente:<\/strong> <a href=\"https:\/\/thedefensepost.com\/2026\/10\/20\/pentagon-chemical-warfare-antidote\/\" target=\"_blank\" rel=\"noopener\"><em>https:\/\/thedefensepost.com<\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>La Agencia de Reducci\u00f3n de Amenazas del Departamento de Defensa de EE.UU., avanza en un contrato de US$ 40 millones a las empresas Battelle y&hellip; <\/p>\n","protected":false},"author":1,"featured_media":19275,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[18,37,24],"tags":[],"_links":{"self":[{"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/posts\/19274"}],"collection":[{"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=19274"}],"version-history":[{"count":1,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/posts\/19274\/revisions"}],"predecessor-version":[{"id":19277,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/posts\/19274\/revisions\/19277"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=\/wp\/v2\/media\/19275"}],"wp:attachment":[{"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=19274"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=19274"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fie.undef.edu.ar\/ceptm\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=19274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}