Métodos para diseñar bacteriófagos genéticamente 

La resistencia a los antibacterianos es un problema emergente en la medicina militar. Las interrupciones en los sistemas de atención médica en países asolados por la guerra que resultan de un conflicto en curso pueden potencialmente exacerbar este problema y aumentar el riesgo para las fuerzas estadounidenses en el entorno de despliegue. Por lo tanto, se necesitan terapias novedosas para mitigar el impacto de estas infecciones potencialmente devastadoras en las operaciones militares.


Introduction
Antibacterial resistance is an emerging problem in military medicine. Disruptions to the health care systems in war-torn countries that result from ongoing conflict can potentially exacerbate this problem and increase the risk to U.S. forces in the deployed environment. Therefore, novel therapies are needed to mitigate the impact of these potentially devastating infections on military operations. Bacteriophages are viruses that infect and kill bacteria. They can be delivered as therapeutic agents and offer a promising alternative to traditional antibiotic chemotherapy. There are several potential benefits to their use, including high specificity and comparative ease of use in the field setting. However, the process of engineering phages for military medical applications can be a laborious and time-consuming endeavor. This review examines available techniques and compares their efficacy.
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Fuente: https://academic.oup.com